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Pablo V Escribá Selected Research

Membrane Lipids

11/2021Fundamentals of Membrane Lipid Replacement: A Natural Medicine Approach to Repairing Cellular Membranes and Reducing Fatigue, Pain, and Other Symptoms While Restoring Function in Chronic Illnesses and Aging.
11/2021Lipids in Pathophysiology and Development of the Membrane Lipid Therapy: New Bioactive Lipids.
4/2019The triacylglycerol, hydroxytriolein, inhibits triple negative mammary breast cancer cell proliferation through a mechanism dependent on dihydroceramide and Akt.
9/2017Membrane-lipid therapy: A historical perspective of membrane-targeted therapies - From lipid bilayer structure to the pathophysiological regulation of cells.
7/2015Membrane lipid therapy: Modulation of the cell membrane composition and structure as a molecular base for drug discovery and new disease treatment.
6/2014Differential effect of 2-hydroxyoleic acid enantiomers on protein (sphingomyelin synthase) and lipid (membrane) targets.
6/2014Regulation of the cancer cell membrane lipid composition by NaCHOleate: effects on cell signaling and therapeutical relevance in glioma.
6/2014The effect of natural and synthetic fatty acids on membrane structure, microdomain organization, cellular functions and human health.
6/2014Membrane lipid modifications and therapeutic effects mediated by hydroxydocosahexaenoic acid on Alzheimer's disease.
5/2013The role of membrane fatty acid remodeling in the antitumor mechanism of action of 2-hydroxyoleic acid.
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Pablo V Escribá Research Topics

Disease

26Neoplasms (Cancer)
11/2021 - 02/2005
8Glioma (Gliomas)
01/2019 - 12/2011
6Alzheimer Disease (Alzheimer's Disease)
01/2020 - 03/2014
5Neurodegenerative Diseases (Neurodegenerative Disease)
01/2020 - 04/2007
4Obesity
09/2017 - 01/2006
4Inflammation (Inflammations)
01/2017 - 01/2006
4Lung Neoplasms (Lung Cancer)
08/2015 - 03/2010
4Hypertension (High Blood Pressure)
06/2014 - 07/2005
2Fatigue
11/2021 - 11/2021
2Pain (Aches)
11/2021 - 01/2017
2Spinal Cord Injuries (Spinal Cord Injury)
09/2017 - 01/2017
1Chronic Disease (Chronic Diseases)
11/2021
1Communicable Diseases (Infectious Diseases)
11/2021
1Pancreatic Neoplasms (Pancreatic Cancer)
01/2021
1Triple Negative Breast Neoplasms
04/2019
1Breast Neoplasms (Breast Cancer)
04/2019
1Glioblastoma (Glioblastoma Multiforme)
01/2019
1Stroke (Strokes)
09/2017
1Neuralgia (Stump Neuralgia)
09/2017
1Contusions
01/2017
1Necrosis
02/2016
1Adult Form Polyglucosan Body Disease
10/2015
1Glycogen Storage Disease Type IV (Andersen's Disease)
10/2015
1Non-Small-Cell Lung Carcinoma (Carcinoma, Non-Small Cell Lung)
08/2015
1Parkinson Disease (Parkinson's Disease)
06/2014
1Pathologic Processes
06/2014
1Sphingolipidoses (Sphingolipidosis)
05/2013
1Body Weight (Weight, Body)
07/2008
1Type 2 Diabetes Mellitus (MODY)
03/2007
1Autoimmune Diseases (Autoimmune Disease)
01/2006
1Adenocarcinoma of Lung
10/2005
1Mental Disorders (Mental Disorder)
08/2004

Drug/Important Bio-Agent (IBA)

14Membrane LipidsIBA
11/2021 - 03/2007
12LipidsIBA
11/2021 - 01/2006
10Fatty Acids (Saturated Fatty Acids)IBA
04/2019 - 03/2007
82-hydroxyoleic acidIBA
01/2019 - 12/2011
8Pharmaceutical PreparationsIBA
08/2015 - 10/2005
6AcidsIBA
08/2021 - 07/2005
5Proteins (Proteins, Gene)FDA Link
11/2021 - 03/2007
5Oleic Acid (Oleate)IBA
01/2017 - 07/2005
4Olive OilIBA
08/2015 - 10/2005
42-hydroxy-9-cis-octadecenoic acidIBA
06/2014 - 02/2005
4SphingomyelinsIBA
05/2013 - 12/2011
3Triglycerides (Triacylglycerol)IBA
01/2021 - 08/2015
3phosphatidylcholine-ceramide phosphocholine transferaseIBA
05/2013 - 12/2011
2hydroxytrioleinIBA
04/2019 - 08/2015
24-hexyloxyaniline (HOA)IBA
01/2017 - 08/2009
2Therapeutic UsesIBA
05/2015 - 06/2014
2Antineoplastic Agents (Antineoplastics)IBA
05/2013 - 10/2005
2Temozolomide (Temodar)FDA LinkGeneric
10/2012 - 05/2012
2Protein Kinase CIBA
03/2010 - 10/2005
1dihydroceramideIBA
04/2019
1Messenger RNA (mRNA)IBA
01/2019
14,7,10,13,16,19-docosahexaenoic acid ethyl esterIBA
09/2017
1Docosahexaenoic AcidsIBA
09/2017
1AlbuminsIBA
01/2017
1Biomarkers (Surrogate Marker)IBA
02/2016
1Ether (Diethyl Ether)IBA
02/2016
1GlycogenIBA
10/2015
1Peptides (Polypeptides)IBA
10/2015
1Mitogen-Activated Protein Kinase 3IBA
08/2015
1Protein Kinases (Protein Kinase)IBA
08/2015
1TrioleinIBA
08/2015
1LigandsIBA
06/2014
1fas Receptor (CD95 Antigen)IBA
06/2014
1Phospholipids (Phosphatides)FDA LinkGeneric
05/2013
1Liposomes (Liposome)IBA
05/2013
1SphingolipidsIBA
05/2013
1Lipid Bilayers (Lipid Bilayer)IBA
05/2013
1Nitric Oxide (Nitrogen Monoxide)FDA Link
01/2013
1Cyclin B1IBA
01/2012
1PalmitatesIBA
01/2012
1DNA (Deoxyribonucleic Acid)IBA
08/2009
1serpentine (alkaloid)IBA
07/2008
1Guanosine Diphosphate (GDP)IBA
07/2008
1NucleotidesIBA
07/2008
1Guanosine Triphosphate (GTP)IBA
07/2008
1Membrane Proteins (Integral Membrane Proteins)IBA
01/2008
1Monounsaturated Fatty AcidsIBA
08/2006
1FatsIBA
07/2005
1Antihypertensive Agents (Antihypertensives)IBA
07/2005

Therapy/Procedure

12Therapeutics
11/2021 - 08/2004
1Oral Administration
05/2012